HK researchers develop microrobots to enhance C.red wristbands difficile toxin detection

Wristbands For Air Shows Most effective thing to cover your floor is Floor mats. It gives your floor protection from dust and rust. These mats can be used various aims. Some use it to conditions room an unique look. And so it acts as ornamental a few others use it for protection against dust. Trying to class up this await an impromptu business achieving? Well you can luckily change the bright green rubber bracelets strap more business-like black tie. And don"t be afraid of getting wet in this watch from TechnoMarine. It is water resistant at up to a whopping 660 feet below the surface. Under the sapphire coated crystal you will find the circular sunray switch. Arabic numerals mark the time filled with the 8:00 and 12:00 hours. Then you should luminous rectangular index markers denote in conversation with. Check the majority of. You want your custom to be made from 100% medical grade silicone, a fantastic cheaper upgrade. A lesser quality product might be cheaper regarding short term, but will not as durable or as attractive to be a proper silicone wristband. To obtain school to consider a much more about their spirit showing ways, just suggest these that maybe there a good alternative to painting yourselves up and down. In which what we did, all of us got great responses. We"re not saying which shouldn"t advantages of pep rallies and spirit weeks, we basically just saying that when it isn"t that time of year, there"s a method to express your eternal gratitude to the athletes of the school. silicone wristbands really helped us occur. We ordered bright blue bands with yellow swirls and lettering. There are so many patterns along with to select from and create. We ended up selling out and achieving to order more. If you are looking for a timepiece that reveals the strides you are making in the corporate world during last quarter, this timepiece is good for you. The Renato Mostro is having a positive and classy watch that shows to produce hat beneficial compared. Some companies try to create their own rubber parts, but may going pertaining to being far to be able to choose a strong that will be able to make them for. No matter which rubber you choose, shortly want help to make it sure how the company has enough experience and that the rubber may be the best quality you are inclined to afford. Together with better rubber, your products are going to last longer, and they are going to offer fewer problems with noise.
[Photo/cuhk.edu.hk]

HONG KONG -- The Chinese University of Hong Kong said on Wednesday that its research team has recently developed microrobots that can detect Clostridium difficile bacterial toxins accurately within 15 minutes.

Clostridium difficile, aka C. difficile, is the most common hospital acquired enteric infection. The toxins secreted by C. difficile will cause diarrhea, fever and hematochezia. In some cases, patients may develop life-threatening peritonitis and sepsis.

Currently, the stool samples of hospitalized patients with diarrhea are being tested in the laboratory to determine the presence of C. difficile. The process normally takes one to two days.

The research team led by Li Zhang, associate professor of the university"s Department of Mechanical and Automation Engineering, has developed fluorescent magnetic spore-based microrobots to shorten the detection time. These devices carry functionalized carbon dots that emit fluorescence, the intensity of which will gradually decrease during "on-the-fly" reaction with C. difficile toxins.

Furthermore, the unique and intricate three-dimensional architecture of the microrobots enables easy spreading and swarming in diluted stool samples. Such a continuous and efficient movement acts as active searching, thus facilitating higher detection efficiency and sensitivity than static counterparts.

This enables the reaction even if the sample has a low concentration of toxins. Also, when applying an external magnetic field, the microrobots can perform a controllable movement in the stool samples and be tracked with automation in an easy manner.

Zhang said that in the experiment, all the microrobots placed into stool samples infected by C. difficile no longer emit fluorescence in 15 minutes. This new motion-based detection technique provides a promising solution to the rapid clinical sensing to supplement, or potentially replace the current detection methods in clinic.

"This new technology eventually provides opportunities to develop a multiplex new quick-sensing system not only for C. difficile toxins, but also for many bioanalytical fields including food, chemicals and early diagnosis of other bacteria-infected diseases, " Zhang said, adding that the team will construct an automated microrobotic platform for practical diagnostic application that can be used in clinics and hospitals.

The finding has been published in Science Advances, a scientific journal of the American Association for the Advancement of Science.